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Nematodes in Sheep: Case Study 1 ('05)

1. Using the data from the 2 samples do a Fecal Egg Count Reduction Test.

Sheep

Pre-EPG

Post-EPG

FECR

1 150 25 83%
2 0 0 NR
3 1500 0 100%
4 0 0 NR
5 1160 280 76%
6 0 0 NR
7 1200 0 100%
8 0 0 NR
9 3850 0 100%
10 143 0 100%
11 1967 0 100%
12 1260 0 100%
13 400 0 100%
14 1217 0 100%
15 1350 0 100%
16 1625 150 91%

The average for the flock was 1322 ± 1079 EPG Pre-Treatment and 36 ± 107 EPG Post-Treatment therefore the FECR was 97%.

Is there any indication that there are nematodes resistant to levamisole on the original farm?

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2. Do you have indication that there may be resistance to ivermectin on the original farm?

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3. What nematodes may have produced the strongyle type eggs that you saw in these sheep? List all nematodes     of Pennsylvania sheep that produce this type of egg.

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4. Name the active ingredients of the drugs approved by the FDA for treating Haemonchus infections in sheep.

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5. What is the approved dose of Levamisole for treating sheep for a Haemonchus infection?

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6. On a farm with multi-drug resistant Haemonchus, what measures can a farmer take to slow down the development of resistance to the one drug which he currently is able to use to control this parasite on his farm?

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Copyright © 2006 - University of Pennsylvania School of Veterinary Medicine, All rights reserved.
Faculty: Dr. Thomas Nolan
Students: Molly Church V'09, Diana Knight V'08, Douglas Gilson V'05, Chris Dykhouse V'04, Kimberly Mah V'00

Comments or Questions contact Dr. Tom Nolan at: