Complete List of Drugs

Extralabel Drug Doses and Withholding Times in Cattle

Drug Class Drug Dosage/Route Usage Meat (days) Milk (hrs) Reference
Anesthetics Bupivacaine Infiltration Rx, ELUD none none (5)
(General & Local Butorphanol (Torbugesic) 0.02-0.05 mg/kg   IV,IM, or SQ Rx, ELUD 2 none (5)
  Fentanyl Injectable or Patch Rx, ELUD 3 none (5)
  Glyceryl guaiacolate/Guaifenesin 50 mg/lb, IV Rx, ELUD none none (5)
  Halothane Inhalation Rx, ELUD none none (5)
  Isoflurane Inhalation Rx, ELUD none none (5)
  Ketamine 2 mg/kg, IV          10 mg/kg, IM Rx, ELUD 3 48 (2)
  Lidocaine w/epinephrine Infiltration, epidural Rx, ELUD 1 24 (2)
  Meperidine Infiltration Rx, ELUD 3 none (5)
  Mepivacaine Infiltration Rx, ELUD none none (5)
  Methoxyflurane Inhalation Rx, ELUD none none (5)
  Morphine IV,IM Rx, ELUD none none (5)
  Oxymorphone IV,IM Rx, ELUD 3 none (5)
  Pentobarbital Oral or Injectable Rx, ELUD 4 4 (5)
  Thialbarbitone 9.4 mg/kg, IV Rx, ELUD 1 24 (2)
  Thiamylal 5.5 mg/kg, IV Rx, ELUD 1 24 (2)
  Thiopental 5-7 mg/lb, IV Rx, ELUD 4 NA (5)
Anthelmintics Albendazole (Valbazan) 10mg/kg, PO OTC 27 NA  
  Amprolium (Corid) 16fl oz/100 gallons water OTC 24h NA  
  Coumaphos (Co-Ral) External duster OTC none none  
  Cydectin 0.5 mg/kg topical OTC 0 unsafe  
  Dectomax 1 ml/110 lbs, IM/SQ OTC 35 NA  
    10ml/220 lbs, topical OTC 45 NA  
  Eprenex 1 ml/10 kg, topical OTC 0 0  
  Ivermectin (Ivomec) 0.2 mg/kg, SQ OTC 35 NA  
  Morantel 10 mg/kg, PO/feed additive OTC none none  
  Fenbendazole (Panacur) 5 mg/kg, PO/topical/mineral block Rx 8 unsafe  
  Phenothiazine 220 mg/kg, PO OTC 7 NA  
  Thiabendazole (TBZ) 66-88 mg/kg, PO OTC 3 96  
  Levamisole (Totalon) 7 mg/kg, SQ ELUD 7 unsafe  
    8 mg/kg, PO ELUD 6 unsafe  
    2.5 ml/110 lbs, topical OTC 9 NA  
Antibiotics Amoxicillin Trihydrate 11 mg/kg, IM/SQ Rx, ELUD 25 96 (6)
    3-5 mg/lb, IM/SQ, q24h Rx      
  Ampicillin Trihydrate 11 mg/kg, Im/SQ Rx, ELUD 6 48 (6)
  Enrofloxacin (Baytril) 7.5-12.5 mg/kg, SQ Rx 28 unsafe  
  Ceftiofur (Naxcel) 2.2 mg/kg, IM        
    0.5-1.0 mg/lb, Im q24h Rx      
  Erythromycin 4.5 mg/kg, Im ELUD 14 72 (6)
    1-2 mg/lb, IM, q24h OTC      
  Ceftiofur (Excenel) 1.1-2.2 mg/kg, IM/SQ, q24h Rx, ELUD 2 unsafe  
  Tilmicosin (Micotil) 10 mg/kg,SQ Rx 28 unsafe  
  Florfenicol (NuFlor) 20 mg/kg, IM, q48h Rx 28 unsafe  
  Oxytetracycline         (4)
       -Injectable,short-acting 6.6-11.0 mg/kg/d, IV/IM ELUD 15-22 156  
  -Injectable,long-acting 6.6-11.0 mg/kg/d, IV/IM ELUD 28 168  
    3-5 mg/lb, Iv/IM, q24h OTC      
  -Intrauterine 1-2 g, IU ELUD 18 168  
    3g, IU ELUD 28    
    4-6g, IU ELUD 35 192  
  -Intramammary 426mg, IMM ELUD 19 96  
  -oral 20-40 mg/kg, PO, q12h, 3-4d ELUD 14 7  
  -preruminant calves 30mg/kg/d, PO, 4d ELUD 21 7  
  Procaine Penicillin G 12,000 iu/lb, IM ELUD 14 (10) 120 (48) (6)
    24,000 iu/lb, IM ELUD 20 ?  
    1 million units/cow, IU, ELUD ? 96  
    3000-5000 IU/lb, IM q24h OTC      
  Spectinomycin (Spectam) 20 mg/kg, IM/SQ OTC, ELUD 60 96 (6)
  Sulfadimethoxine (Di-Methox) 55 mg/kg, IV initially followed by 27 mg/kg, IV q24h OTC 5 60 (6)
  (Albon 55 mg/kg, PO initially, followed by 27 mg/kg, PO ELUD 7 60  
    25 mg/lb IV initially followed by 12.5 mg/lb, q24h OTC      
  Trimethoprim + Sulfadiazine 4 mg TMP +20 mg SDZ/kg, PO Rx, ELUD 28 0 (6)
  (Di-Trim) 4 mg TMP +20 mg SDZ/kg, IM/IV Rx, ELUD 28 168  
  Tylosin (Tylan) 18 mg/kg, IM OTC, ELUD 21 96 (6)
Antibiotic (topical) Gentamicin 5 mg/kg,IV/IM/SQ Rx,ELUD 18 mon. 120 (6)
  Neomycin 10 mg/lb, IM/SQ/IU OTC     (6)
NSAIDS Aspirin 100mg/kg PO q 12 h OTC 1 24 (3)
  Dipyrone Not approved       (3)
  Flunixin meglumine (Banamine) 1.1-2.2 mg/kg, IV/IM q 24h, 3-5d Rx, ELUD 10 72 (3)
    1/100lbs, IM/IV,q24h Rx      
  Ketoprofen (Ketofen) 3.3mg/kg,IV/IM,q24h,3d Rx, ELUD 7 24 (3)
  Phenylbutazone 6g/animal,IV/IM Rx, ELUD 12 96 (3)
    9mg/kg, IV/PO; 4.5 mg/kg, IV/PO Rx, ELUD 21 120 (6)
Corticosteroids Dexamethasone 0.05-0.1 mg/kg, IM/IV Rx 0 0 (6)
  Predef 2x 10-20 mg/kg,IM/IV OTC,ELUD 0 0  
  Solu-Delta-Cortef 0.1-0.2 mg/kg, IM/IV Rx,ELUD 0 0  
Insecticides Chlorpyrifos (Screw worm) Ear Tick Spray, topical OTC 0 0 (1)
  Copper naphthenate (Koppertox) topical OTC 0 0 (1)
  Copper sulfate (Proudoff) topical OTC 0 0 (1)
  Coumaphos (Coral) topical OTC 10 10 (1)
  Famphur (Warbex) topical OTC 35 10 (1)
  Fenthion (Spotton) topical OTC 35-45 10 (1)
  Formaldehyde topical OTC 0 0 (1)
  Lindane (Screw worm,aerosol-L) topical OTC 0 0 (1)
  Methoxychlor (Purina Cattle Dust) topical OTC 0 0 (1)
  Nitrofurazone (Furacin) topical OTC 0 0 (1)
  Permethrin (Ectiban EC) topical OTC 0 0 (1)
  Phosmet (Prolate) topical OTC 1 0 (1)
  Tetracyclines topical OTC 0 0 (1)
  Trichlorfon (Neguvon) topical OTC 21   (1)
Sedative/Tranquilizers Acepromazine 0.13 mg/kg,IV; 0.44 mg/kg IM Rx,ELUD 7 48 (2)
  Chloral hydrate 20-30 mg/lb,IV Rx,ELUD none none (5)
  Detomidine 0.08 mg/kg, IM/IV Rx,ELUD 3 72 (2)
  Diazepam 0.01-0.04 mg/lb, IV Rx,ELUD >2 none (5)
  Guafenesin(Guailaxin) 100 mg/kg,IV Rx,ELUD 3 48 (2)
  Xylazine 0.016-0.1 mg/kg,IV Rx,ELUD 5 72 (2)
    0.05-0.3 mg/kg,IM Rx,ELUD 5 72 (2)
    0.3-2.0 Mg/kg,IM Rx,ELUD 10 120 (2)
Sedative Reversal Agent Yohimbine 0.3 mg/kg,IV Rx,ELUD 7 72 (2)

References

1.  Baynes, R.E., A.L. Craigmill, and J.E. Riviere. 1997. Residue avoidance after topical application of veterinary drugs and parasiticides [published erratum appears in J Am Vet Med Assoc 1997 Aug 1,211(3):304]. J Am Vet Med Assoc. 210:1288-9.

2.  Craigmill, A.L., M. Rangel-Lugo, P. Damian, and J. E. Riviere. 1997. Extralabel use of tranquilizers and general anesthetics. J Am Vet Med assoc. 211:302-4.

3.  Damian, P., A. L. Craigmill, and J. E. Riviere. 1997. Extralabel use of nonsteroidal anti-inflammatory drugs [see comments]. J Am Vet Med Assoc. 211:860-1.

4.  Martin-Jimenez, T., A. L. Craigmill, and J. E. Riviere. 1997. Extralabel use of oxytetracycline. J Am Vet Med Assoc. 211:42-4.

5.  Papich, M. G. 1996. Drug residue considerations for anesthetics and adjunctive drugs in food-producing animals. Vet Clin North Am Food Anim Pract. 12:693-706.

6.  Payne, M. A. 1991. Extralabel drug use and withdrawal times in dairy cattle. Compendium on Continuing Education for the Practicing Veterinarian. 13:1341-1351.

 

 

Copyright 1999-2001
New Bolton Center Field Service Department
Students:  Keith Javic - Class of 2003, C. Nikki Conroy - Class of 2003