Chemical group: Isoquinoline-pyrazine
Trade name: Cestex
Mode of action: Unknown, may interfere with calcium metabolism leading to detachment and disruption of the tegument.
Pharmacokinetics: Poorly absorbed from gut. Leaves host in feces as parent compound.
Dose: Cat: 2.75 mg/kg (Use in cats over 7 weeks of age.)
Dog: 5.5 mg/kg (Use in dogs over 7 weeks of age)
Toxicity: Minimum lethal dose in rats was greater than 5000 mg/kg. No adverse reactions seen in kittens given 29.9 mg/kg and none in puppies given 100 mg/kg.
Parasite Targets: Tapeworms
© University of Pennsylvania 2004
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