Subungual Keratoacanthoma
(NAILBED KERATOACANTHOMA)
A benign neoplasm of the nailbed epithelium which may cause lysis of the
phalangeal bone.
Histology:
•Symmetrical, unencapsulated tumor with irregular scalloped borders
•Central core of keratin
•Wall of the tumor composed of sheets of keratinocytes that have an abundant pale eosinophilic cytoplasm with distinct borders and large
vesicular nuclei
•There is no granular layer
•Central aggregates of keratin are often parakeratotic
•Variable number of apoptotic keratinocytes may be found
 |
|
Sex Distribution (N=85) |
||||||||
| Sex | Status |
Percent |
||||||
|
|
30.6 | ||||||
|
20.0 | |||||||
|
|
16.5 | ||||||
|
32.9 | |||||||
| Anatomic Location (N=46) | |
| Site |
Percent |
| Forelimb | 58.7 |
| Hindlimb | 31.3 |
