Eccrine Carcinoma
A malignant tumor showing differentiation to eccrine secretory epithelium.
Gross Appearance:
Arise on the foot pads. An infiltrative nodular neoplasm.
Histology:
•Very uncommon tumor
•Differentiation of eccrine carcinoma from apocrine carcinoma is exceedingly
difficult and requires knowledge of the site of origin of the tumor (footpad in
dog and cat) for a definitive diagnosis
•Neoplastic cells may have a pale eosinophilic cytoplasm and small
hyperchromatic nuclei, suggesting thaey are differentiating to eccrine glandular
epithelium
•In the dog, the glandular, papillary or cribiform aggregates of carcinoma
cells are surrounded by a sclerotic stroma
•Must be differentiated from metastatic carcinomas
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