Anal Sac Gland Carcinoma
A simple malignant tumor showing differentiation to apocrine secretory epithelium, arising in the wall of the anal sac.
Gross Appearance:
•Vary in size from 0.5-8.0 cm in diameter
•Smallest tumors only identified on rectal digital palpation
•Large masses mimic gross appearance of hepatoid gland adenomas
•May be ulcerated
•Metastasis to sacral and sublumbar lymph nodes may cause difficulty in urination and defecation
•Hypercalcemia secondary to pseudohyperthyroidism presents as polyuria and polydipsia
 |
Histology:
Three patterns, which represent varying degrees of differentiation of the tumor, may be
found
| Breeds At Increased Risk | |||
| Breed | Odds Ratio | 95% Confidence Limit | Probability |
| Siamese | 12.8 | 6.26 - 26.41 | 0.001 |
