Liposarcoma
A malignant tumor of lipocytes with variable pleomorphism and little or no collagenous stroma.
Gross Appearance:
•Vary in color from white (similar to lipomas) to orange or green
•Areas of hemorrhage and necrosis
Histology:
•Highly cellular tumor
•Degree of differentiation is variable
Well differentiated type
•Closely simulates a lipoma
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Pleomorphic type
• Marked degree of nuclear and cellular pleomorphism
•Intracytoplasmic lipid vacuoles
• Mitoses are common and often atypical
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Myxoid type
•Lipocytes lying in a myxoid matrix
•Pleomorphic type
•Marked degree of nuclear and cellular pleomorphism
•Intracytoplasmic lipid vacuoles
•Mitoses are common and often atypical
