Liposarcoma (Myxoid)

Liposarcoma

A malignant tumor of lipocytes with variable pleomorphism and little or no collagenous stroma.

Gross Appearance:
•Vary in color from white (similar to lipomas) to orange or green
•Areas of hemorrhage and necrosis

Histology:
•Highly cellular tumor
•Degree of differentiation is variable

Well differentiated type
•Closely simulates a lipoma

Pleomorphic type
•Marked degree of nuclear and cellular pleomorphism
•Intracytoplasmic lipid vacuoles
•Mitoses are common and often atypical

Myxoid type
•Lipocytes lying in a myxoid matrix
•Pleomorphic type
•Marked degree of nuclear and cellular pleomorphism
•Intracytoplasmic lipid vacuoles
•Mitoses are common and often atypical

Cytology:

Sex Distribution (N=297)

Sex Status
Percent

Male
(45.0%)

52.2%

intact
(28.1%)

34.7

neutered
(16.9%)

17.5

Female
(55.0%)

47.8%

intact
(23.9%)

17.5

neutered
(31.1%)

30.3

(normal sex distribution)

Anatomic Location (N=291)

Site
Percent

Head 7.2

Neck 4.8

Forelimb 24.0

Hindlimb 24.0

Abdomen 9.2

Thorax 20.8

Back 3.4

Multiple 0.3

Tail 2.2

Perineum 4.1